| San Francisco Giants | | | | | | | | Trade |
| Arizona Diamondbacks | Anthony Rizzo Byron Buxton Willson Contreras | | | LF, RF, SP | | | Mon, Apr 29 | Trade |
| Atlanta Braves | | | | | | | | Trade |
| Baltimore Orioles | | | | | | | | Trade |
| Boston Red Sox | Giancarlo Stanton Mitch Haniger | | | 2B | | | Sun, Apr 21 | Trade |
| Chicago Cubs | Bryson Stott Randy Arozarena | | | RF | | | Sun, Mar 10 | Trade |
| Cleveland Indians | | | | | | | | Trade |
| Detroit Tigers | | | | | | | | Trade |
| Los Angeles Angels | | | | | | | | Trade |
| Los Angeles Dodgers | | | | | | | | Trade |
| Miami Marlins | | | | | | | | Trade |
| New York Mets | | | | | | | | Trade |
| New York Yankees | Alex Verdugo Nolan Gorman Michael Kopech José Soriano Ricky Tiedemann | | | 3B, SP, RP | | | Thu, May 30 | Trade |
| Oakland Athletics | | | | | | | | Trade |
| Philadelphia Phils | | | | | | | | Trade |
| Pittsburgh Pirates | Trevor Story José Berríos Dustin May Jordan Montgomery | | | RP | SV | | Sun, Mar 3 | Trade |
| ST Louis Cardinals | | | | | | | Tue, Jun 4 | Trade |
| Tampa Bay Rays | | | | | | | | Trade |
| Texas Rangers | | | | | | | | Trade |
| Toronto Blue Jays | Andrés Giménez Luis Robert Jr. Steven Kwan Jeff McNeil | LF, CF | | 1B, 2B, SS | | | Sun, Jun 16 | Trade |
